Important elements of rational drug design. Ligand-receptor interactions, structure-activity relationships, molecular modeling of pharmacophores, structure and mechanism-based approaches to drug design. Enzyme inhibition in chemotherapy and design of anti-viral drugs. Prerequisite(s): CHEM 2103 and (CHEM 2203 or CHEM 2207), BIOC 3101 and (BIOC 3102 or BIOC 3008).Lectures and laboratory five hours a week.